Science can only explain what is measurable. I don't think it requires very much imagination to imagine that there is a lot we are missing or overlooking. This doesn't mean that science isn't incredibly useful and offer an incredible amount of value for improving the quality of our lives. It's just a statement that science is not truth and reasonable skepticism is healthy. Doubt is at the core of every belief, secular and religious.  Faith too is always necessary, even if it is imperceptible - in everything we do. Faith and doubt are nothing but probability assessments.